Interaction of anesthetic supplement thiopental with human serum albumin.
نویسندگان
چکیده
منابع مشابه
Interaction of anesthetic supplement thiopental with human serum albumin.
Thiopental (TPL) is a commonly used barbiturate anesthetic. Its binding with human serum albumin (HSA) was studied to explore the anesthetic-induced protein dysfunction. The basic binding interaction was studied by UV-absorption and fluorescence spectroscopy. An increase in the binding affinity (K) and in the number of binding sites (n) with the increasing albumin concentration was observed. Th...
متن کاملRegular paper Interaction of anesthetic supplement thiopental with human serum albumin
Thiopental (TPL) is a commonly used barbiturate anesthetic. Its binding with human serum albumin (HSA) was studied to explore the anesthetic-induced protein dysfunction. The basic binding interaction was studied by UV-absorption and fluorescence spectroscopy. An increase in the binding affinity (K) and in the number of binding sites (n) with the increasing albumin concentration was observed. Th...
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ژورنال
عنوان ژورنال: Acta Biochimica Polonica
سال: 2008
ISSN: 1734-154X,0001-527X
DOI: 10.18388/abp.2008_3088